New Equivalence Tests for Hardy–Weinberg Equilibrium and Multiple Alleles
نویسندگان
چکیده
منابع مشابه
Equivalence Tests
Scientists should be able to provide support for the absence of a meaningful effect. Currently, researchers often incorrectly conclude an effect is absent based a nonsignificant result. A widely recommended approach within a frequentist framework is to test for equivalence. In equivalence tests, such as the two one-sided tests (TOST) procedure discussed in this article, an upper and lower equiv...
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An equivalence test example will set the stage for the discussion of the terminology that follows. Suppose that the response rate of the standard treatment of a disease is 0.70. Unfortunately, this treatment is expensive and occasionally exhibits serious side-effects. A promising new treatment has been developed to the point where it can be tested. One of the first questions that must be answer...
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We discuss the possible existence of new long-range forces mediated by spin-1 or spin-0 particles. They would add their effects to those of gravity, and could lead to apparent violations of the Equivalence Principle. Informations on the (vector and axial) couplings of a new spin-1 U boson may be obtained from spontaneously broken gauge invariance. The charge associated with the vector coupling ...
متن کاملThe HardyWeinberg Package
This guide gives some instructions on how to perform graphical significance tests for HardyWeinberg equilibrium (HWE) by depicting the acceptance region for HWE in a ternary plot with routines from the package HardyWeinberg. The outline of this guide is as follows. Section 2 describes how the R package HardyWeinberg can be installed. Section 3 shows how to perform some of the classical tests fo...
متن کاملEquivalence Tests for Paired Means (Simulation)
This procedure allows you to study the power and sample size of tests of equivalence of means of two correlated variables. Schuirmann’s (1987) two one-sided tests (TOST) approach is used to test equivalence. The paired t-test is commonly used in this situation. Other tests have been developed for the case when the data are not normally distributed. These additional tests include the Wilcoxon si...
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ژورنال
عنوان ژورنال: Stats
سال: 2020
ISSN: 2571-905X
DOI: 10.3390/stats3010004